Author

Matthew T James

Queen's University BelfastORCID 0009-0008-5361-4803Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

Aurélie MousnieriD· 2 shared Courtney DaneiD· 2 shared Aidan FerrisiD· 1 shared Aidan O’RiainiD· 1 shared Alanna O MooreiD· 1 shared Andrea Goya GrociniD· 1 shared Caoimhe McAuleyiD· 1 shared David CourtneyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Aurélie MousnierORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 17, 2026

The heat shock protein 70 (Hsp70) family of chaperones is essential for rhinovirus replication

Matthew T James, Courtney Dane, Alanna O Moore, Aurélie Mousnier

This study shows Hsp70 chaperones are essential for rhinovirus replication and identifies them as potential broad-spectrum antiviral targets.

DOI 10.64898/2026.08.13.742791

humanexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivPreprintMay 14, 2026

A host ATPase essential for rhinovirus replication is an antiviral target with a high barrier to resistance

Matthew T James, Courtney Dane, Karolina Wojtania…·Aurélie Mousnier

This study identifies RUVBL1/2 as a host ATPase essential for rhinovirus replication and shows that its inhibition effectively blocks viral replication without resistance development.

DOI 10.64898/2026.05.13.723454

humanexperimental assay

𝕏 PostBluesky