Author

David Courtney

Queen's University BelfastORCID 0000-0002-0677-1194Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 2 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

E. M. P. E. GettyiD· 4 shared Ultan F. PoweriD· 4 shared Emily Peate· 2 shared Hannah L CouttsiD· 2 shared Hannah L. Turkington· 2 shared Stefano BonazzaiD· 2 shared Swathi SukumariD· 2 shared Aidan FerrisiD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersMicrobiology

E. M. P. E. GettyORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A host ATPase essential for rhinovirus replication is an antiviral target with a high barrier to resistance

Matthew T James, Courtney Dane, Karolina Wojtania, Caoimhe McAuley, Andrea Goya Grocin, Remigiusz Adam Serwa, Michael L. Glenn, Erin M P E Getty, Aidan O’Riain, Jack W. Houghton, Aidan Ferris, Sheerien Manzoor, David Courtney, Ultan F. Power, Edward W. Tate, Aurélie Mousnier

This study identifies RUVBL1/2 as a host ATPase essential for rhinovirus replication and shows that its inhibition effectively blocks viral replication without resistance development.

bioRxiv · May 14, 2026 · PreprintMicrobiology

Age-dependent expression and antiviral activity of interferon epsilon in respiratory epithelium

Mary McCabe, Helen Elizabeth Groves, Erin M P E Getty, Emma Campbell, Connor Bamford, David G. Courtney, Guillermo López–Campos, Michael David Shields, Ultan F. Power

This study shows that IFNE expression decreases in infants, leading to reduced antiviral activity against RSV, suggesting a role in early-life RSV susceptibility.

Journal of Virology · May 12, 2026Peer-reviewedMicrobiology

Myoferlin is an essential component of late-stage vRNP trafficking vesicles for enveloped RNA viruses.

Stefano Bonazza, Hannah L. Turkington, Swathi Sukumar, Emily Peate, Hannah L Coutts, Joshua J Montgomery, Courtney Hawthorn, E. M. P. E. Getty, Olivier Touzelet, Judit Barabas, Ultan F. Power, David Courtney

The paper identifies myoferlin as a conserved host factor essential for late-stage vRNP trafficking in enveloped RNA viruses like IAV, RSV, and SeV.

Nature Communications · Feb 7, 2026Peer-reviewedMicrobiology

The cold-inducible RNA-binding protein RBM3 stabilises viral mRNA at the cooler temperatures of the upper respiratory tract.

Hannah L Coutts, Swathi Sukumar, Hannah L. Turkington, Stefano Bonazza, Emily Peate, E. M. P. E. Getty, Ultan F. Power, David G Courtney

This study identifies RBM3 as a host factor that stabilizes influenza A virus mRNA at cooler temperatures, enhancing viral replication in the upper respiratory tract.

bioRxiv · Jul 25, 2024 · PreprintMicrobiology

Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique

Cecilia Martinez Campos, Kevin Tsai, David Courtney, Hal P. Bogerd, Christopher L. Holley, Bryan R. Cullen

The paper introduces PA-{Psi}-seq, a technique to map pseudouridine residues on cellular and viral transcripts, and shows that HIV-1 transcripts are not affected by PUS enzyme inactivation.

RNA · Aug 10, 2021Peer-reviewedMolecular Biology