Ikuto Nishikawa

This study identifies Il1r2 as a marker for slow-cycling epidermal basal cells and develops a genetic tool for lineage tracing and IL-1 signaling modulation.

This study shows that RUNX1-ETO expression in keratinocytes causes progressive skin inflammation through transcriptional dysregulation and activation of inflammatory pathways.

The paper shows that IL-1 signaling suppresses Wnt activity in epidermal stem cells during inflammation, leading to changes in stem cell compartments that can be reversed by Wnt reactivation.

This study investigates how undulating tissue structures influence epithelial stem cell heterogeneity in skin and oral mucosa using mouse models and 3D culture systems.