Developmental BiologybioRxivPreprint
Inflammatory IL-1 signaling remodels epidermal stem cell compartments by suppressing Wnt activity
Hung Manh Phung, Ikuto Nishikawa, Nguyen Thi Kim Nguyen…·Aiko Sada
The paper shows that IL-1 signaling suppresses Wnt activity in epidermal stem cells during inflammation, leading to changes in stem cell compartments that can be reversed by Wnt reactivation.