Natalie Quan

The paper tests if protein misfolding causes collateral fitness effects from mutations and finds it is not common, but misfolding does drive primary fitness costs when function is essential.

This paper uses subcellular proteomics to show that glycolytic and gluconeogenic enzymes are mosaically localized in Paramecium tetraurelia, with some enzymes in mitochondria and others in the cytosol, suggesting a preference for gluconeogenesis.