ImmunologybioRxivPreprint
Dexamethasone inhibits the LPS-induced activation of hypoxia-inducible factor 1 alpha (HIF-1α) in macrophages independently of the DUSP1-p38-TTP-HIF-1α regulatory axis.
Chloe Lockwood, Kalbinder K Daley, John D. O’Neil…·Andrew R. Clark
This study shows dexamethasone inhibits LPS-induced HIF-1α activation in macrophages through a glucocorticoid-sensitive mechanism, independent of the DUSP1-p38-TTP-HIF-1α pathway.
1 citation