Adriano Marchese

This study investigates how receptor phosphorylation and membrane lipids cooperatively control arrestin activation, identifying key phospho-motifs and lipid interactions.

This study compares the membrane-binding properties of arrestin-2 and arrestin-3 using biophysical and cell-based methods, revealing distinct lipid interaction mechanisms and activation dynamics.

This study shows that CXCL12-LD, a dimeric variant of the chemokine, reduces chemotaxis in AML cells by altering receptor signaling and internalization, suggesting potential for improved CXCR4 targeting.