Cancer BiologybioRxivPreprint
Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state
Christine Chiasson-MacKenzie, Youwen Zhang, Evan O’Loughlin…·Andrea I. McClatchey
This study shows that different FGFR2 mutations in cholangiocarcinoma affect biliary architecture based on the epithelial state of the cells, revealing distinct phenotypic consequences.