Author

Jovan Isma

Harvard UniversityORCID 0009-0008-8580-4169Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Anna MandinovaiD· 1 shared Atul KatarkariD· 1 shared Cyril PulveriD· 1 shared Emery Di CiccoiD· 1 shared G. Paolo Dotto· 1 shared Gaetana RestivoiD· 1 shared Gian Paolo DottoiD· 1 shared Heather A. Harrington· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Anna MandinovaORCID

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2 papers

Recent·Most cited

Cancer BiologyScience AdvancesPeer-reviewedOct 2, 2026

A TERRA–NONO Axis Drives Fibroblast Reprogramming in Cancer

Emery Di Cicco, Jovan Isma, Stefano Sol…·Gian Paolo Dotto

This study identifies the TERRA-NONO axis as a driver of fibroblast reprogramming into cancer-associated fibroblasts, showing its therapeutic potential in multiple cancers.

DOI 10.1126/sciadv.aed3358

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintJan 9, 2025

Topology identifies concurrent cyclic processes in single-cell transcriptomics and androgen receptor function

Kelly Maggs, Markus K. Youssef, Cyril Pulver…·G. Paolo Dotto

The paper introduces a topological framework to detect and disentangle multiple cyclic processes from single-cell transcriptomic data, validated on synthetic datasets and biological samples.

DOI 10.1101/2025.01.09.632214

humanmouse

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