BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Atomic resolution map of the solvent interactions driving SOD1 unfolding in CAPRIN1 condensates
Rashik Ahmed, Mingyang Liang, Rhea P. Hudson…·Lewis E. Kay
This study uses NMR to show CAPRIN1 condensates shift SOD1 folding towards unfolded states, promoting aggregation, while a zinc-bound dimeric form is more stable.
19 citations