Rhea P. Hudson

This paper shows that CAPRIN1 condensates suppress FUS RRM aggregation despite increasing its concentration and unfolding it, by outcompeting homotypic intermolecular contacts.

This study shows that protein interactions, calcium, phosphorylation, and cholesterol regulate CFTR cluster formation on membranes through multivalent interactions and phase separation.

This study uses NMR to show CAPRIN1 condensates shift SOD1 folding towards unfolded states, promoting aggregation, while a zinc-bound dimeric form is more stable.