BiochemistryJournal of Biological ChemistryPeer-reviewed
Understanding the Pathogenicity of Parkin Catalytic Domain Mutants
Julian P. Wagner, Véronique Sauvé, Anshu Saran, Kalle Gehring
The paper investigates two pathogenic parkin mutations in the RING2 domain, showing impaired ubiquitin binding and activity through biochemical assays and AlphaFold modeling.
10 citations