TMEDs Mediate Versatile Cargo Transport in Vesicle-dependent Unconventional Secretion
Jianfei Zheng, Haodong Wang, Yuxin Sun, Pei Chang, Xing Deng, Lijingyao Zhang, Lin Zhu, Kangling Zhu, Dong Peng, Haiteng Deng, Min Zhang, Liang Ge
This study identifies TMED proteins as key regulators of vesicle-dependent unconventional secretion, showing they mediate cargo selectivity through translocation and oligomerization.
The Journal of Cell Biology · Oct 21, 2025Peer-reviewedCell Biology