Author

Yuxin Sun

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Assay:CUT&Tag· 1 Research Focus:drug response / drug discovery· 1 Assay:Hi-C· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Chen ZhangiD· 4 shared Chong TangiD· 4 shared Fengying Ruan· 4 shared Mei Li GuoiD· 4 shared Weitian CheniD· 4 shared Yaning LiiD· 4 shared Yeming XieiD· 4 shared Yitong FangiD· 4 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Chen ZhangORCID

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Author profile →

5 papers

Recent·Most cited

A patient-centric therapeutic paradigm uncouples prostate cancer suppression from systemic metabolic collapse

Ziqun Liu, Hanchu Ye, Haoran Hu, Wuhong Chen, Chen Wang, Yongfeng Yang, Xinran Yan, Longlong Chen, Yang Wang, Yumeng Yang, Chunqiao Sun, Yaqing Bai, Haiyang Hou, Xinan Wang, Jun Cao, , Zhenfei Li

This paper identifies metabolic dysregulation caused by abiraterone in prostate cancer patients and develops Lifehug-9892 to suppress tumors while preserving systemic metabolic health.

bioRxiv · Sep 2, 2026 · PreprintCancer Biology

Spatial chromatin accessibility sequencing resolves high-order spatial interactions of epigenomic markers

Yeming Xie, Fengying Ruan, Yaning Li, Meng Luo, Chen Zhang, Zhichao Chen, Zhe Xie, Zhe Weng, Weitian Chen, Wenfang Chen, Yitong Fang, Yuxin Sun, Mei Li Guo, Juan Wang, Shouping Xu, , Chong Tang

This study introduces SCA-seq to resolve spatial chromatin interactions at single-molecular resolution and demonstrates its application in analyzing epigenomic markers.

eLife · Jan 18, 2024Peer-reviewedGenomics

High coverage of single cell genomes by T7-assisted enzymatic methyl-sequencing

Juan Wang, Yitong Fang, Wenfang Chen, Chen Zhang, Zhichao Chen, Zhe Xie, Zhe Weng, Weitian Chen, Fengying Ruan, Yeming Xie, Yuxin Sun, Mei Li Guo, Yaning Li, Chong Tang

This study introduces TEAM-seq, a method for high-coverage 5mC sequencing in single cells, achieving 70% coverage at 100pg input DNA.

bioRxiv · Feb 23, 2022 · PreprintGenomics

Long-range single-molecule mapping of chromatin modification in eukaryotes

Zhe Weng, Fengying Ruan, Weitian Chen, Zhe Xie, Yeming Xie, Chen Zhang, Zhichao Chen, Juan Wang, Yuxin Sun, Yitong Fang, Mei Li Guo, Yiqin Tong, Yaning Li, Chong Tang

The paper introduces a method called BIND&MODIFY to map histone modifications at the single-molecule level using long-read sequencing, revealing long-range chromatin states and heterogeneity.

bioRxiv · Jul 8, 2021 · PreprintGenomics

Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure.

Weitian Chen, Zhe Weng, Zhe Xie, Yeming Xie, Chen Zhang, Zhichao Chen, Fengying Ruan, Juan Wang, Yuxin Sun, Yitong Fang, Mei Li Guo, Yiqin Tong, Yaning Li, Chong Tang

The paper introduces CCDA-seq to study ecDNA chromatin structure, revealing distinct nucleosome and regulator binding patterns.

bioRxiv · Mar 31, 2021 · PreprintGenomics