Jennifer L. Sinclair

This study shows that elevated temperature worsens arrhythmia and seizures in a zebrafish model of Timothy syndrome, suggesting fever may increase risk for TS patients.

The paper shows that parp1 deletion rescues cerebellar hypotrophy in xrcc1 mutant zebrafish, suggesting PARP1 inhibition could be therapeutic for neurological disorders.

The paper generates and annotates new Cre transgenic zebrafish lines for intersectional genetic experiments and integrates them with a brain atlas for spatial search.