Author

Yanru Zhang

Hainan Vocational University of Science and TechnologyORCID 0009-0009-0450-2001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Bing HaniD· 1 shared Chunxia LiuiD· 1 shared Fang WaniD· 1 shared Fanhua Meng· 1 shared Hongmei Xiao· 1 shared Huanmin ZhouiD· 1 shared Junwei CaoiD· 1 shared Lu LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Bing HanORCID

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1 paper

Recent·Most cited

Lactate metabolism antagonizes antiviral innate immunity bypromoting VDAC1-lactylation-mediated mtDNA release

Yi Wu, Lu Li, Yiyi Liu, Shenyuan Wang, Fanhua Meng, Tao Li, Hongmei Xiao, Fang Wan, Yingchun Liu, Bing Han, Huanmin Zhou, Chunxia Liu, Yanru Zhang, Junwei Cao

This study shows FMDV infection in horse cells increases lactate, which modifies VDAC1 and promotes mtDNA release, activating cGAS-STING and reducing viral replication.

bioRxiv · May 9, 2025 · PreprintCell Biology