Author

Leo Epstein

Gladstone InstitutesORCID 0009-0009-0607-854XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Leo Epstein1 paper · Max Delbrück Center

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Organism:human· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam C. WeineriD· 2 shared Barbara Elizabeth EngelhardtiD· 2 shared Alexander MarsoniD· 1 shared Archit VermaiD· 1 shared Bria L MackliniD· 1 shared Bruce R. ConkliniD· 1 shared Julia C. CarnevaleiD· 1 shared Kaitlin R KellyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Adam C. WeinerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 17, 2026

Using image classifiers to predict CMT2A disease-relevant mitochondrial motility phenotypes in iPSC motor neurons

Leo F. Epstein, Adam C. Weiner, Bria L Macklin…·Barbara Elizabeth Engelhardt

This paper develops a vision transformer framework to classify CMT2A disease phenotypes in iPSC motor neurons using kymographs, showing improved accuracy over traditional metrics.

DOI 10.64898/2026.03.16.712192

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 4, 2025

Live-cell analyses with unsegmented images to study cancer cell response to modified T cell therapy

Leo Epstein, Adam C. Weiner, Archit Verma…·Barbara Elizabeth Engelhardt

This paper introduces a segmentation-free method to analyze live-cell imaging data of T cell-cancer cell interactions, revealing how T cell modifications affect aggregate formation dynamics.

DOI 10.1101/2025.06.04.657687

𝕏 PostBluesky