Author

Leire Extramiana

NavarrabiomedORCID 0009-0009-0900-8328Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Enrique SantamaríaiD· 3 shared Joaquín Fernández‐IrigoyeniD· 3 shared Marina De Miguel· 3 shared Paz Cartas‐CejudoiD· 3 shared Silvia Romero-MurilloiD· 3 shared Mercedes Lachén‐MontesiD· 2 shared Andrea A. Felizardo-Otalvaro· 1 shared Djordje O. GvericiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Enrique SantamaríaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceBrain PathologyPeer-reviewedAug 30, 2026

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α-synuclein preformed fibrils-induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

Paz Cartas‐Cejudo, Marina De Miguel, Leire Extramiana…·Enrique Santamaría

The paper uses proteomic analysis of the olfactory tract to identify pyroxamide, an HDAC1 inhibitor, as a potential therapeutic for Parkinson's disease by reducing α-synuclein fibril-induced toxicity in cell lines.

DOI 10.1111/bpa.70140

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMar 16, 2026

Multi-omics characterization of SIRT3 metabolism and its adaptation to the presence of amyloid-beta oligomers in nasal epithelial cells

Paz Cartas‐Cejudo, Marina De Miguel, Silvia Romero-Murillo…·Enrique Santamaría

The paper investigates the role of SIRT3 in nasal epithelial cell metabolism under amyloid-beta oligomer exposure using multi-omic approaches and identifies sex-dependent SIRT protein level differences in neurological disorders.

DOI 10.64898/2026.03.13.711520

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 26, 2025

Early, sex-dependent and progressive proteomic imbalance in the amygdala during Alzheimers disease progression

Silvia Romero-Murillo, Mercedes Lachén‐Montes, Paz Cartas‐Cejudo…·Enrique Santamaría

This study identifies sex-dependent and progressive proteomic changes in the amygdala across Alzheimer's disease stages, revealing potential sex-specific biomarkers and therapeutic targets.

DOI 10.1101/2025.11.26.690815

humanproteomics

𝕏 PostBluesky