Author

I Pavel

Babeș-Bolyai UniversityORCID 0009-0009-1577-2867Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Manuela BanciuiD· 3 shared Alina SesărmaniD· 2 shared Emilia LicăreteiD· 2 shared Laura PătrașiD· 2 shared Marta Szilvia MeszarosiD· 2 shared Stefan DraganiD· 2 shared Alejandro Bernabeu Martinez· 1 shared Ana MeleroiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

Manuela BanciuORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 1, 2026

Extracellular Vesicles Derived from Activated Dendritic Cells Loaded with Curcumin Promote Early Activation-associated Functional and Molecular Reprogramming of Primary CD8+ T Cells

Stefan Dragan, Laura Pătraș, Marta Szilvia Meszaros…·Alina Sesărman

This study shows that curcumin-loaded dendritic cell-derived extracellular vesicles enhance early activation of CD8+ T cells by promoting effector-like phenotypes and sustained molecular reprogramming.

DOI 10.64898/2026.06.30.735629

mouseproteomics

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Cancer BiologybioRxivPreprintJul 1, 2026

Fibroblast-Enhanced Tumour Microenvironment Signalling Promotes Adaptive Doxorubicin Tolerance in Heterotypic Melanoma Spheroids

I Pavel, Giorgiana Negrea, Marta Szilvia Meszaros…·Manuela Banciu

This study shows fibroblasts in melanoma spheroids enhance doxorubicin tolerance by altering transcriptional responses, promoting stress-adaptive states over classical resistance mechanisms.

DOI 10.64898/2026.06.30.735445

humanbulk RNA-seq

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Pharmacology & ToxicologybioRxivPreprintApr 1, 2025

Transcriptomic insights into early diagnosis of doxorubicin-induced cardiotoxicity in a rat model

Emilia Anca, Ilie-Ovidiu Pavel, Emilia Licărete…·Manuela Banciu

This study identifies transcriptomic changes in a rat model of doxorubicin-induced cardiotoxicity, revealing metabolic dysregulation and circadian rhythm disruption that may inform early diagnostic biomarkers.

1 citation

ratbulk RNA-seq

𝕏 PostBluesky