Author

Rishi Soni

Johns Hopkins UniversityORCID 0009-0009-2516-2229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

James W. McCormickiD· 1 shared Jerry C. DinaniD· 1 shared Kimberly A. ReynoldsiD· 1 shared Samuel ThompsoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

James W. McCormickORCID

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintAug 25, 2026

Protein Surface Site Determines the Evolutionary Accessibility of Allosteric Regulation

Jerry C. Dinan, James W. McCormick, Rishi Soni…·Kimberly A. Reynolds

This study shows that inserting a domain into a protein's sector-connected surface increases the likelihood of evolving allosteric regulation, while non-sector-connected sites are less evolvable.

DOI 10.64898/2026.07.02.735819

protein structuredeep learning

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