BioengineeringNature CommunicationsPeer-reviewed
Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing
David N. Fiflis, Nicolas A. Rey, Harshitha Venugopal-Lavanya…·Aravind Asokan
This study repurposes CRISPR-Cas13 systems to enable trans-splicing of exogenous RNA fragments into endogenous pre-mRNA, improving editing of large mRNA segments in mammalian cells.
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