Francesca R. Napoli

This study characterizes a LacZ knock-in/knock-out allele at the Vsx2 locus in mice, revealing its role in retinal development and identifying potential incomplete knock-out effects.

The paper uses live-imaging to show that squid retinal neurogenesis shares vertebrate-like mechanisms, including interkinetic nuclear migration and Notch signaling regulation.

The paper identifies the co-option of the bilaterian limb patterning program in cephalopod lens development, showing similar gene expression and regulatory mechanisms with reversed Wnt signaling.