Author

Jacob E. Valk

University of WashingtonORCID 0009-0009-3712-7973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Dan J. WoodcockiD· 2 shared Elena BaraznenokiD· 2 shared Eric Quentin KonnickiD· 2 shared Freddie Charles HamdyiD· 2 shared Huai-Ching HsiehiD· 2 shared Ian Geoffrey MillsiD· 2 shared Jonathan T.C. LiuiD· 2 shared Sandy FigieliD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Dan J. WoodcockORCID

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2 papers

Recent·Most cited

BioengineeringNature MethodsPeer-reviewedJun 22, 2026

3D pathology-guided microdissection

Huai-Ching Hsieh, Gan Gao, Qinghua Han…·Jonathan T.C. Liu

This paper introduces a 3D microdissection method combining CNC milling and light-sheet microscopy to study tumor evolution in complex 3D structures.

3 citationstop 4%

imagingexperimental assay

𝕏 PostBluesky

PathologyLaboratory InvestigationPeer-reviewedJun 16, 2026

Assessing the effects of a 3D pathology tissue-processing workflow on downstream molecular analyses

Elena Baraznenok, Huai-Ching Hsieh, Lydia Lan…·Jonathan T.C. Liu

This study evaluates the impact of a 3D pathology workflow on DNA, RNA, and protein integrity, showing minimal effect on amplifiability and transcriptomic profiles.

1 citation

humanDNA methylation

𝕏 PostBluesky