Author
Jonathan T.C. Liu
University of WashingtonORCID 0000-0001-5650-3086Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 7/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links9 papers
Recent·Most cited
- PathologybioRxivPreprint
Scalable 3D cell-interaction analysis via supercell graphs for prostate cancer risk stratification
Yujie Zhao, Sarah S. L. Chow, Renao Yan…·Jonathan T.C. Liu
SCALE3D improves prostate cancer risk prediction by analyzing 3D cell interactions through supercell graphs, outperforming traditional features and reducing computational demands.
DOI 10.64898/2026.07.07.736891 - BioengineeringNature MethodsPeer-reviewed
3D pathology-guided microdissection
Huai-Ching Hsieh, Gan Gao, Qinghua Han…·Jonathan T.C. Liu
This paper introduces a 3D microdissection method combining CNC milling and light-sheet microscopy to study tumor evolution in complex 3D structures.
3 citationstop 4% - PathologyLaboratory InvestigationPeer-reviewed
Assessing the effects of a 3D pathology tissue-processing workflow on downstream molecular analyses
Elena Baraznenok, Huai-Ching Hsieh, Lydia Lan…·Jonathan T.C. Liu
This study evaluates the impact of a 3D pathology workflow on DNA, RNA, and protein integrity, showing minimal effect on amplifiability and transcriptomic profiles.
1 citation - BioengineeringbioRxivPreprint
High-throughput, organ-scale 3D tubule tracking using TubuleMAP
Chetan Poudel, David Brenes, Wenhui Xie…·Joshua C. Vaughan
The paper introduces TubuleMAP, a semi-automated 3D tubule tracking pipeline for analyzing tubular networks, achieving high throughput and accuracy in reconstructing kidney and testis tubules.
- BioengineeringScience AdvancesPeer-reviewed
LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecture
Wesley B. Fabyan, Chelsea L. Fortin, Dorice Laura Goune…·Kelly R. Stevens
The paper uses 3D imaging to analyze human liver tissue and identifies spatial dysregulation in cirrhotic vasculobiliary architecture.
- PathologyModern PathologyPeer-reviewed
Detection of prostate cancer in 3D pathology datasets via generative immunolabeling
Robert Serafin, Jennifer Salguero López, SP Chow…·Jonathan T.C. Liu
This paper develops a 3D computational pipeline called SIGHT to detect prostate cancer in pathology datasets using generative immunolabeling, achieving an F1 score comparable to pathologist agreement.
- PathologybioRxivPreprint
Deep-learning triage of 3D pathology datasets for comprehensive and efficient pathologist assessments
Gan Gao, Renao Yan, Andrew H. Song…·Jonathan T.C. Liu
CARP3D uses deep learning to prioritize high-risk 2D sections in 3D pathology data, improving disease detection while reducing pathologist workload.
6 citations