Assessing the effects of a 3D pathology tissue-processing workflow on downstream molecular analyses
Elena Baraznenok, Huai-Ching Hsieh, Lydia Lan, Eric Quentin Konnick, Sandy Figiel, Srinivasa R. Rao, Dan J. Woodcock, Ian Geoffrey Mills, Freddie Charles Hamdy, Jacob E. Valk, Kelly T. Carter, Ming Yu, Thomas G. Paulson, Suzanne M. Dintzis, William M. Grady, Jonathan T.C. Liu
This study evaluates the impact of a 3D pathology workflow on DNA, RNA, and protein integrity, showing minimal effect on amplifiability and transcriptomic profiles.
Laboratory Investigation · Jun 16, 2026Peer-reviewedPathology