Zhengqing Li

This paper introduces a metalloprotein framework that acts as an atomic ruler to separate adjacent rare-earth elements with high selectivity and stability.

The paper determines the crystal structures of Clr4 bound to ubiquitinated and unmodified H3 peptides, revealing how H3K14 ubiquitination synergistically enhances Clr4 catalytic activity through conformational changes and multivalent interactions.