Author

Chaimae Benkerdagh

Christian-Albrechts-Universität zu KielORCID 0009-0009-5038-4448Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Marcus ScheweiD· 2 shared Thomas BaukrowitziD· 2 shared Berke TürkaydiniD· 1 shared Francesco Luigi GervasioiD· 1 shared Han SuniD· 1 shared Karin E. J. RödströmiD· 1 shared Matilda DevliniD· 1 shared Mehtab S. HayreiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

Marcus ScheweORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiophysicsbioRxivPreprintOct 28, 2026

A Binding Site for CVN293 Reveals a Mechanism for Allosteric Control of THIK-1 K2P Channel Gating

Matilda Devlin, Karin E. J. Rödström, Chaimae Benkerdagh…·Stephen J. Tucker

This study identifies the binding site of CVN293 on THIK-1 K2P channel and reveals its allosteric inhibition mechanism through cryoEM structures and functional validation.

DOI 10.64898/2026.10.27.761881

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 14, 2026

Energetic cross-talk of filter gate and lower helices drives polymodal regulation and disease in TREK K2P channels

Berke Türkaydin, Valerio Rizzi, Chaimae Benkerdagh…·Han Sun

This study uses molecular dynamics to analyze TREK-2 channel conformational changes, linking them to disease mechanisms and drug discovery.

DOI 10.64898/2026.02.13.705734

electrophysiologymechanistic / dynamical model

𝕏 PostBluesky