Author
University of Eastern FinlandORCID 0009-0009-5249-9038Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Heli Jeskanen, Sami Heikkinen, Inka Kervinen…·Mikko O. Hiltunen
The paper examines how protective PLCG2 variants delay Alzheimer's onset in APOE ε4 carriers and identifies associated plasma biomarkers.
Mari Takalo, Heli Jeskanen, Taisia Rõlova…·Mikko Hiltunen
This study shows that the PLCgamma2-P522R variant reduces beta-amyloid pathology and enhances microglial function in AD models, suggesting an anti-ageing mechanism.
Audrey Coulon, Florian Rabiller, Mari Takalo…·Jean‐Charles Lambert
This study shows that PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease-related markers in neurons.