Author

Inka Kervinen

University of Eastern Finland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Annakaisa HaapasaloiD· 2 shared Heli JeskaneniD· 2 shared Henna MartiskaineniD· 2 shared Mari TakaloiD· 2 shared Roosa-Maria WillmaniD· 2 shared Sami HeikkineniD· 2 shared Ville LeinoneniD· 2 shared Alfredo Ramı́reziD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Annakaisa HaapasaloORCID

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2 papers

Recent·Most cited

The protective PLCG2 variants delay Alzheimer's disease onset age in APOE ϵ4 carriers

Heli Jeskanen, Sami Heikkinen, Inka Kervinen, Jenni Lehtisalo, Tiia Ngandu, Roosa-Maria Willman, Jéssica Rosa, Dorit B. Hoffmann, FinnGen, Ville Leinonen, Annakaisa Haapasalo, Mari Takalo, Henna Martiskainen, Mikko O. Hiltunen

The paper examines how protective PLCG2 variants delay Alzheimer's onset in APOE ε4 carriers and identifies associated plasma biomarkers.

medRxiv · Sep 22, 2025 · PreprintGenetic & Genomic Medicine

Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions

Mari Takalo, Heli Jeskanen, Taisia Rõlova, Inka Kervinen, Marianna Hellén, Sami Heikkinen, Henna Koivisto, Kimmo T. Jokivarsi, Stephan A. Müller, Esa-Mikko Koivumäki, Petra M. Mäkinen, Sini-Pauliina Juopperi, Roosa-Maria Willman, Rosa Sinisalo, Dorit Hoffman, , Mikko Hiltunen

This study shows that the PLCgamma2-P522R variant reduces beta-amyloid pathology and enhances microglial function in AD models, suggesting an anti-ageing mechanism.

bioRxiv · Sep 12, 2024 · PreprintNeuroscience