Stephanie J. Georges

The paper identifies a rare Tcf4 lineage-negative stem cell population in the colon that contributes to wound repair and colon tumorigenesis when Apc is deleted.

The paper benchmarks somatic variant and indel detection at low allele fractions using short- and long-read data, finding sensitivity and precision around 80% at 300x coverage.

gene.iobio is a web tool that enables clinicians and researchers to interactively analyze and prioritize genomic variants for clinical diagnosis and patient care.