Bruna Filipa Correia

The paper identifies a novel immunosuppressive neutrophil subset, CCR4+LDN, associated with breast cancer progression and mortality, and shows its potential as a biomarker and therapeutic target.

This study investigates the clinical impact of immunosuppressive low-density neutrophils in metastatic breast cancer, finding they correlate with faster disease progression and reduced survival.

This study shows that enhancing HLA-DR expression in cytotoxic T lymphocytes improves their anti-tumor activity, suggesting strategies to optimize adoptive T cell therapies for breast cancer.