Cell BiologyThe FASEB JournalPeer-reviewed
Wnt activation in mature dermal adipocytes leads to lipodystrophy and skin fibrosis via ATGL-dependent lipolysis.
Qiannan Ma, Ella X. Segal, Miles A. Montegut…·Radhika P. Atit
This study shows that Wnt activation in mature dermal adipocytes causes lipodystrophy and skin fibrosis, which can be reversed by stopping Wnt activation.