Sean Boult

This study investigates how environmental factors and mutations affect the stability and scalability of catch bond complexes between SdrG and fibrinogen beta chain using single-molecule and multi-valent adhesion assays.

The paper investigates the mechanical properties of the Izumo1:Juno complex using force spectroscopy and simulations, revealing its mechanostability and how mutations affect it.

The paper uses enzyme proximity sequencing to map how mutations affect substrate specificity of DAOx, identifying key positions and combinations that enhance selectivity.