Author

Fraser James Pirie

University of KwaZulu-NatalORCID 0009-0009-6420-3855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:fine-mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:polygenic risk· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Ayesha Ahmed MotalaiD· 2 shared Segun FatumoiD· 2 shared Tinashe ChikoworeiD· 2 shared Adebowale AdeyemoiD· 1 shared Andrew P. MorrisiD· 1 shared Charles N. RotimiiD· 1 shared Dipender GilliD· 1 shared Elizabeth H. Young· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Ayesha Ahmed MotalaORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintNov 26, 2025

Multi-ancestry fine-mapping accounting for ancestral and environmental heterogeneity improves resolution and interpretation

Siru Wang, Oyesola Oyewole Ojewunmi, Fraser James Pirie…·Jennifer L. Asimit

The paper introduces two fine-mapping methods to account for ancestral and environmental heterogeneity in GWAS, improving resolution of causal variants across diverse populations.

DOI 10.1101/2025.11.26.690727

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsbioRxivPreprintFeb 11, 2021

Polygenic Prediction of Type 2 Diabetes in Continental Africa

Tinashe Chikowore, Kenneth Ekoru, Marijana Vujković…·Segun Fatumo

This study evaluates if African American or multi-ethnic polygenic risk scores improve type 2 diabetes prediction in continental Africans, finding that African American-derived scores are more predictive.

3 citations

humanwhole-exome sequencing

𝕏 PostBluesky