Author

Xiaotong Ma

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0009-0009-7892-4143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Alexei VerkhratskyiD· 1 shared Can Hui YangiD· 1 shared Cheng-Ya Dong· 1 shared Fu‐Dong ShiiD· 1 shared Gusheng TangiD· 1 shared Jianfei FuiD· 1 shared Jing XueiD· 1 shared Junwan FaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alexei VerkhratskyORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 1, 2025

Targeting HMGA1-driven leukemic transformation in myeloproliferative neoplasms with pacritinib

Can Hui Yang, Yajun Li, Kun Chen…·Zhiyuan Wu

This study identifies HMGA1 as a critical driver of MPN progression to sAML, showing it outperforms existing markers and is targeted by pacritinib to improve survival.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 23, 2024

Elastase mediated white matter damage in cerebral small vessel disease: Microglia - neutrophils pas de deux

Cheng-Ya Dong, Weiqi Chen, Qi Li…·Wei-Na Jin

This study identifies elastase (ELANE) as a driver of white matter damage in cerebral small vessel disease, showing its role in oligodendrocyte death and proposing it as a therapeutic target.

DOI 10.1101/2024.12.23.630204

mouseexperimental assay

𝕏 PostBluesky