Author

Yuta Sakai

Daiichi-Sankyo (Japan)ORCID 0009-0009-7967-705XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Christopher B. BurgeiD· 2 shared Emma J. K. KowaliD· 2 shared Michael P. McGurkiD· 2 shared Elaine HuangiD· 1 shared Zoe J. Pasetsky· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Christopher B. BurgeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GeneticsbioRxivPreprintSep 29, 2026

The strength of a gene's first 5' splice site is a key determinant of its expression

Yuta Sakai, Michael P. McGurk, Emma J. K. Kowal…·Christopher B. Burge

The paper shows that the strength of a gene's first 5' splice site determines its expression level through intron-mediated enhancement, independent of 3' splice site strength.

DOI 10.64898/2026.09.28.754465

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintOct 29, 2024

Sequence determinants of intron-mediated enhancement learned from thousands of random introns

Emma J. K. Kowal, Yuta Sakai, Michael P. McGurk…·Christopher B. Burge

This study identifies sequence features that determine intron-mediated enhancement by analyzing thousands of synthetic introns in human cells.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky