Emma J. K. Kowal

The strength of a gene's first 5' splice site is a key determinant of its expression

The paper shows that the strength of a gene's first 5' splice site determines its expression level through intron-mediated enhancement, independent of 3' splice site strength.

Sequence determinants of intron-mediated enhancement learned from thousands of random introns

This study identifies sequence features that determine intron-mediated enhancement by analyzing thousands of synthetic introns in human cells.

Identification of markers for the isolation of neuron-specific extracellular vesicles

The paper identifies NRXN3 as a neuron-specific marker for isolating extracellular vesicles from biofluids and develops methods to isolate these vesicles for neurological disease research.

L1CAM is not Associated with Extracellular Vesicles in Human Cerebrospinal Fluid or Plasma

The paper shows L1CAM is not associated with extracellular vesicles in human plasma or CSF and provides tools to evaluate other markers for NDEV isolation.