Author

Yutaka Takeo

Yale UniversityORCID 0009-0009-8198-2870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Danielle F. MiyagishimaiD· 2 shared Declan McGuoneiD· 2 shared Jennifer A. MoliternoiD· 2 shared Ketu Mishra-GoruriD· 2 shared Murat GüneliD· 2 shared Phan Q. DuyiD· 2 shared Tanyeri BarakiD· 2 shared Zeynep Erson-OmayiD· 2 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersCancer Biology

Danielle F. MiyagishimaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 17, 2026

Multicellular Spatial Programs Define the Histopathological Architecture of Meningioma

Danielle F. Miyagishima, Arman Afrasiyabi, Declan McGuone…·Murat Günel

This study identifies multicellular spatial molecular programs in meningiomas using multi-omic data and develops a model to infer these programs from histopathology.

DOI 10.64898/2026.06.16.732172

humanscRNA-seq

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NeuroscienceeLifePeer-reviewedApr 18, 2023

Microcephaly-associated WDR62 mutations hamper Golgi apparatus-to-spindle pole shuttling in human neural progenitors

Claudia Dell’Amico, Marilyn M. Angulo Salavarria, Yutaka Takeo…·Marco Onorati

This study shows that WDR62 mutations disrupt Golgi-to-spindle pole shuttling in neural progenitors, leading to neurodevelopmental abnormalities in microcephaly.

15 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintAug 24, 2022

spARC Recovers Human Glioma Spatial SignalingNetworks with Graph Filtering

Manik Razdan Kuchroo, Danielle F. Miyagishima, Holly R. Steach…·Smita Krishnaswamy

The paper introduces spARC, a method to recover spatial signaling networks in gliomas, revealing an Osteopontin-CD44 interaction enriched in grade IV astrocytomas.

6 citations

humanspatial transcriptomics

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