GenomicsMolecular MicrobiologyPeer-reviewed
CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis
Matthew B. McNeil, Laura M. Keighley, Josephine R. Cook…·Gregory Murray Cook
This study uses CRISPR interference to assess the vulnerability and lethality of 96 target genes in Mycobacterium tuberculosis, identifying bactericidal and bacteriostatic effects across different cellular pathways.