Author

Lauren L. Ott

Mayo ClinicORCID 0009-0009-9109-317XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Danielle M. BurgenskeiD· 3 shared Jann Nagina SarkariaiD· 3 shared Brandon A. WilbanksiD· 2 shared Brett L. CarlsoniD· 2 shared Caroline D. DohertyiD· 2 shared Katie Bakken· 2 shared Louis James Maher IIIiD· 2 shared Sonia JainiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersBiochemistry

Danielle M. BurgenskeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 26, 2026

Approaches to optimize cell internalization and in vivo tumor homing by aptamer-drug conjugates using SELEX

Caroline D. Doherty, Sonia Jain, Katie Bakken…·Louis James Maher III

This study explores optimizing aptamer-drug conjugates for GBM treatment by focusing on internalization and tumor homing through in vivo SELEX, but faces challenges with tumor specificity.

DOI 10.64898/2026.08.25.747018

humanexperimental assay

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Systems BiologyNature CommunicationsPeer-reviewedAug 8, 2026

Uncovering the signaling networks of disseminated glioblastoma cells in vivo with INSIGHT

Ryuhjin Ahn, Alicia D. D’Souza, Lawrence Long…·Forest M. White

The paper introduces INSIGHT, a platform for phosphoproteomic analysis of rare cell subpopulations, and applies it to study signaling changes in disseminated glioblastoma cells in vivo.

1 citation

mouseproteomics

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Cancer BiologyNAR CancerPeer-reviewedJul 27, 2026

In Vivo Selection of anti-glioblastoma DNA aptamer-drug conjugates in an orthotopic patient-derived xenograft model

Caroline D. Doherty, Sonia Jain, Lauren L. Ott…·Louis James Maher III

This study develops and tests DNA aptamer-drug conjugates (ApDCs) for glioblastoma treatment using an in vivo SELEX approach in a patient-derived xenograft model.

1 citation

mouseexperimental assay

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