Genomic investigation of a suspected multi-drug resistant Klebsiella pneumoniae outbreak in a neonatal care unit in sub-Saharan Africa
Jennifer CornickiD, Patrick MusichaiD, Chikondi PenoiD, Ezgi SeageriD, Pui‐Ying Iroh TamiD, Sithembile Bilima, Aisleen BennettiD, Neil KennedyiD, Nicholas FeaseyiD, Eva HeinziD, Amy K. CainiD
Abstract
A suspected outbreak of multi-drug resistant (MDR) Klebsiella pneumoniae in a Malawian neonatal unit was investigated using whole-genome sequencing. Strain-types, virulence and resistance genes of K. pneumoniae isolated from patients from the hospital over a four-year period were identified. A MDR ST340 clone was implicated as the likely outbreak cause.
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