Nature CommunicationsBiophysicsPeer-reviewed journal article
Nano-org, a functional resource for single-molecule localisation microscopy data
Sandeep ShirgilliD, Daniel J. NievesiD, Jeremy Andrew PikeiD, Mahmoud A. AhmediD, H. Abbott, Mohammed BaragillyiD, Kylie SavoyeiD, Jonathan D. WorboysiD, Khodor S. HazimeiD, Ezra BruggemaniD, A. Lopez Garcia, David J. WilliamsoniD, Patrick Rubin‐DelanchyiD, Ruby PetersiD, Daniel M. DavisiD, Ricardo HenriquesiD, Steven F. LeeiD, Dylan M. OweniD
Abstract
We present a publicly accessible, curated, and functional resource, termed "nano-org", containing single-molecule localisation microscopy (SMLM) data representing the nanoscale distributions of proteins in cells. Nano-org is searchable by comparing the statistical similarity of the datasets it contains. This unique functionality allows the resource to be used to understand the relationships of nanoscale architectures between proteins, cell types or conditions, enabling a new field of spatial nano-omics.
- assay: imaging
- research focus: cell type annotation
- research focus: spatial domain detection
- approach: experimental assay
- Citations
- 5
- FWCI
- 1.61
- Field percentile
- top 16%
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