Daniel J. Nieves

SynthMLM generates synthetic localisation data for SMLM using interpretable structural descriptors from experimental data, enabling benchmarking and testing of analysis methods.

This paper introduces a contrastive learning framework for nanoscale spatial-omics, enabling analysis of single-molecule localisation data to study protein architecture and its changes under various conditions.

Nano-org provides a curated resource of single-molecule localisation microscopy data for studying protein nanoscale distributions and their relationships across cell types and conditions.

This study identifies early atrial remodelling as a driver of arrhythmia in Fabry Disease by combining ECG analysis, iPSC-derived cardiomyocytes, and in-silico modelling.

This study investigates how MBNL proteins and RNA decay pathways regulate mutant DMPK mRNA in DM1, showing that their absence reduces RNA foci and promotes mRNA degradation.