COBREXA.jl: constraint-based reconstruction and exascale analysis
Miroslav KratochvíliD, Laurent HeirendtiD, St. Elmo WilkeniD, Taneli PusaiD, Sylvain ArreckxiD, Alberto NoronhaiD, Marvin van AalstiD, Venkata SatagopamiD, Oliver EbenhöhiD, Reinhard SchneideriD, Christophe TrefoisiD, Wei GuiD
Abstract
COBREXA.jl is a Julia package for scalable, high-performance constraint-based reconstruction and analysis of very large-scale biological models. Its primary purpose is to facilitate the integration of modern high performance computing environments with the processing and analysis of large-scale metabolic models of challenging complexity. We report the architecture of the package, and demonstrate how the design promotes analysis scalability on several use-cases with multi-organism community models. Availability and implementationhttps://doi.org/10.17881/ZKCR-BT30. Contactchristophe.trefois@uni.lu, wei.gu@uni.lu
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