bioRxivMicrobiologyPreprint
Growth of Paracoccus aminovorans is restricted by L-ascorbic acid (LA) and human gut isolate
Kiran Heer, Pratanu KayetiD, Nandita Sharma, Surajit BasakiD, Saumya RaychaudhuriiD
Abstract
Gut microbiota plays a crucial role in the outcome of cholera. In this context, Paracoccus aminovorans, a gut commensal, has been evidenced to positively influence the pathogenesis of cholera bacterium. In the present study, we examined the impact of various non-antibiotic strategies on the growth of Paracoccus aminovorans. We observed the growth of Paracoccus aminovarans was severely restricted in the presence of L-ascorbic acid as well as in co-culture growth assays with another gut commensal, Weissella confusa.
- Citations
- 0
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Understanding the physiological alterations of Vibrio cholerae upon exposure to L-ascorbic acid
Manpreet Kaur, Sakshi Gautam, … Saumya Raychaudhuri·bioRxiv·Sep 3, 2026
- L-Ascorbic acid restricts Vibrio cholerae survival in various growth conditions
H. Sen, M. Kaur, S. Raychaudhuri·bioRxiv·Apr 7, 2023
- Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement
K. Barrasso, D. Chac, … W.-L. Ng·bioRxiv·Feb 1, 2021
- In vivo efficacy of L-ascorbic acid in restricting cholera pathogenesis
Prolay Halder, Himanshu Sen, … Hemanta Koley·bioRxiv·Apr 1, 2025
- L-ascorbic acid (vitamin C) fermentation by the human pathogen Vibrio cholerae
J. R. Rosenberger, N. D. McDonald, E. F. Boyd·bioRxiv·Sep 8, 2020
- Enterocloster citroniae and related gut microbiome species modulate Vibrio cholerae biofilm formation through the production of bioactive small molecules
Heidi Pauer, Saeideh Nasiri, … L. Caetano M. Antunes·VirulencePeer-reviewed·Sep 16, 2026