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Microbial Production Of Ellagic Acid From Mango Pulp Processing Waste

R. Anandan, M. Athiappan, V. Kannan

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Abstract

Ellagic acid has gained momentum recently due to its various properties like anti-mutagenic, anti-carcinogenic, anti-oxidant, and anti-viral and many other benefits to human health. The present study focused on the microbial production of ellagic acid from mango pulp processing industrial waste an alternate method for conventional chemical extraction. Our experiments demonstrated that the 100 g/ml of ellagic acid was produced by Micrococcus luteus from 9% of mango pulp waste and the optimization of ellagic acid production with Pontecorvo medium supplemented with 5.0 g of ellagitannin has yielded 37.80 {+/-} 0.30 mg/g at pH 5.0, temperature 30 {degrees}C, ammonium nitrate (nitrogen source), glucose (carbon source), with 1.5% of inoculums after 24 h of incubation. Ellagic acid synthesized was further confirmed with the standard ellagic acid. Applications like drought resistant in plants, anti-microbial activity, anti-parasitic activity and anti-cancer activities have been proven. Ellagic acid exhibited potential applications and further research in product development is promising.

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M. Athiappan, R. Anandan, V. Kannan+1 more·bioRxiv·Mar 17, 2020