Largus Theodora Angenent

This study improves methane yield from formate and hydrogen co-feeding by engineering a methanogen to bypass hydrogen-induced genetic regulation of formate metabolism.

This paper establishes the FAST tag as a fluorescent reporter in Methanothermobacter thermautotrophicus, showing temperature-dependent instability and growth phase-dependent promoter regulation.

This paper demonstrates the production of acetoin from H2 and CO2 in Methanothermobacter thermautotrophicus using an inducible promoter system, achieving stable acetoin yields in continuous cultivation.

This paper develops a continuous bioreactor to maintain stable nasal microbiomes from swab specimens and synthetic communities, showing long-term stability and S. aureus decolonization.

This study converts bakery waste into n-caproate and n-caprylate using microbial chain elongation, achieving 30-35% carbon conversion with lactate as a superior intermediate.

This paper develops a genetic system for Clostridium kluyveri to enable heterologous production of n-butanol and n-hexanol through modified alcohol dehydrogenases.

The paper constructs synthetic nasal communities to study how community composition influences metabolic competition and S. aureus colonization resistance.

MMonitor provides real-time analysis and visualization of metagenomic data, enabling dynamic microbiome research through automated pipelines and interactive dashboards.

This study compares D- and L-lactate consumption by gut microbes, finding distinct microbial communities and metabolic pathways for each isomer.

This study evaluates the toxicity and biodegradation of HTL process waters from food-waste and wheat straw feedstocks in anaerobic digestion, showing feedstock-specific impacts and the effectiveness of microaeration.

This study compares liquid- and vapor-fed anode zero-gap bioelectrolysis cells for electromethanogenesis, finding similar CH4 production rates but advantages of vapor-fed systems in reducing catalyst degradation.

The paper shows that tyrosine availability influences Staphylococcus aureus nasal colonization and its interactions with commensal bacteria.

This study deletes AOR genes in C. ljungdahlii and shows changes in ethanol and acetic acid production with different carbon sources.

This study compares reactor configurations for lactate production from acid whey, finding that a CSTR with a hollow-fiber membrane module achieved the highest conversion efficiency and rate.

This study identifies operational conditions to steer microbiomes toward producing specific medium-chain carboxylates, finding that ethanol-to-lactate ratios and temperature influence product specificity.

This study identifies oxygen's role in enabling renewable n-caprylate production from ethanol and acetate via intermediate metabolite synthesis in bioreactors.

This study evaluates the performance of three electrode materials during shutdowns in microbial electrochemical systems for electromethanogenesis, finding that nickel cathodes show the fastest recovery.

This paper describes a microbial system to produce folate from renewable energy and CO2, achieving 6.7 mg of folate per 100 g biomass with zero or negative net-carbon emissions.

This study investigates how H2 and O2 levels in open-culture reactors affect n-caproate and n-caprylate production and microbiota composition.

This paper develops a CRISPR-based base-editing tool for acetogenic bacteria to enable precise single-nucleotide modifications without DNA cleavage, improving gene editing efficiency.