bioRxivMicrobiology
Microbiome and Antimicrobial Resistance Gene Dynamics in International Travelers
C. Langelier, M. Graves, K. L. Kalantar, S. Caldera, R. Durrant, M. Fisher, R. Backman, W. Tanner, J. DeRisi, D. Leung
Abstract
We engaged metagenomic next generation sequencing to longitudinally assess the gut microbiota and antimicrobial resistomes of international travelers to understand global exchange of resistant organisms. Travel resulted in an increase in antimicrobial resistance genes and a greater proportion of Escherichia species within gut microbial communities without impacting diversity.
- organism: human
- assay: metagenomics
- research focus: ecology & biodiversity
- approach: experimental assay
Reproducibility ledger
Nobody has reported trying to reproduce this paper yet. Did you replicate an experiment or run the code? Your report saves the next lab a week.
Sign in to file a reproducibility report.
Related papers
- Insights into global antimicrobial resistance dynamics through the sequencing of enteric bacteria from U.S. international travelers
Sushmita Sridhar, Colin J. Worby, … Ashlee M. Earl·The Journal of Infectious DiseasesPeer-reviewed·Sep 19, 2025
- The intestinal microbiota predisposes to traveller’s diarrhoea and to the carriage of multidrug-resistant Enterobacteriaceae after travelling to tropical regions
S. Leo, V. Lazarevic, … E. Ruppe·bioRxiv·Feb 14, 2018
- Real-time sampling of travelers shows intestinal colonization by multidrug-resistant bacteria to be a dynamic process with multiple transient acquisitions
A. Kantele, E. Kuenzli, … A. McNally·bioRxiv·Jan 23, 2020
- Recovery of the gut microbiome following enteric infection and persistence of antimicrobial resistance genes in specific microbial hosts
Z. A. Hansen, K. A. Vasco, … S. D. Manning·bioRxiv·Jan 13, 2023
- Antibiotic treatment drives the diversification of the human gut resistome
J. Li, E. Rettedal, … M. O. A. Sommer·bioRxiv·Feb 1, 2019
- Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota
B. Kintses, O. K. Mehi, … C. Pal·bioRxiv·Aug 7, 2018