Author

S. D. Manning

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Organism:human· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Organism:virus· 2 Organism:chicken / avian· 1

Frequent Co-Authors

C. R. McCutcheon· 2 shared D. M. Aronoff· 2 shared J. Gaddy· 2 shared K. A. Vasco· 2 shared L. Zhang· 2 shared B. Bowcutt· 1 shared B. Norby· 1 shared H. D. Davies· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

C. R. McCutcheon

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Genomic adaptation in group B Streptococcus following intrapartum antibiotic prophylaxis and childbirth

M. E. Pell, H. M. Blankenship, J. A. Gaddy, H. D. Davies, S. D. Manning

This study identifies genomic adaptations in group B Streptococcus (GBS) following intrapartum antibiotic prophylaxis, showing increased mutation rates and biofilm production in persistent colonizers.

bioRxiv · Apr 1, 2024Evolutionary Biology

Persistent effects of intramammary ceftiofur treatment on the gut microbiome and antibiotic resistance in dairy cattle

K. A. Vasco, S. Carbonell, R. E. Sloup, B. Bowcutt, R. R. Colwell, K. Graubics, R. Erskine, B. Norby, P. L. Ruegg, L. Zhang, S. D. Manning

This study examines the effects of intramammary ceftiofur treatment on dairy cattle gut microbiome and antibiotic resistance, finding persistent changes in microbiome abundance and resistance gene abundance up to 9 weeks post-treatment.

bioRxiv · Jul 17, 2023Microbiology

Recovery of the gut microbiome following enteric infection and persistence of antimicrobial resistance genes in specific microbial hosts

Z. A. Hansen, K. A. Vasco, J. T. Rudrik, K. T. Scribner, L. Zhang, S. D. Manning

This study examines the gut microbiome and antimicrobial resistance gene dynamics before and after enteric infection, finding higher resistance gene diversity during infection and shifts in microbial composition post-recovery.

bioRxiv · Jan 13, 2023Microbiology

Group B streptococcal membrane vesicles induce proinflammatory cytokine production and are sensed in an NLRP3 inflammasome-dependent mechanism in human macrophages

C. R. McCutcheon, J. Gaddy, D. M. Aronoff, S. D. Manning, M. G. Petroff

This study shows that GBS membrane vesicles induce proinflammatory cytokines in macrophages via NLRP3 inflammasome-dependent mechanisms, suggesting potential for immunotherapeutic targeting.

bioRxiv · Aug 10, 2022 · PreprintImmunology

Production and composition of group B streptococcal membrane vesicles varies across diverse lineages

C. R. McCutcheon, J. Gaddy, D. M. Aronoff, M. Petroff, S. D. Manning

This study quantifies membrane vesicle production and protein composition across diverse GBS strains, finding lineage-dependent variation in MVs that may influence clinical outcomes.

bioRxiv · Aug 24, 2021Microbiology