Karanjin alters gene expression through ERα: a preliminary study
Abstract
Karanjin is an abundant furanoflavonoid-constitutent of pongamia oil. Among several biological actions of karanjin, the antiproliferative effect of karanjin has gained traction in the recent years; raising speculations about its anticancer potential. In the backdrop of partial estrogen-like alteration of gene expression by karanjin in ER positive MCF-7 breast cancer cells, we present preliminary evidences supporting of the role of ER in karanjin-mediated effects.
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